Though Lofton was born with a limp (from which he derived his stage name), he actually started his career as a tap-dancer. Lofton moved on from tap-dancing into the blues idiom known as boogie-woogie and moved on to perform in Chicago, Illinois.
With his distinctive performance style, Lofton found himself a mainstay in his genre: His first recording was in April 1935 for Vocalion Records with guitar accompaniment from Big Bill Broonzy. He later went on to own the Big Apple nightclub in Chicago and continued to record well into the late 1940s, when he retired. Lofton lived in Chicago until he died from a blood clot in his brain in Cook County Hospital in 1957.
Lofton was an integral part of the boogie-woogie genre in Chicago. Some of his more popular songs include: "Strut That Thing", "Monkey Man Blues", "I Don't Know" and "Pitchin' Boogie". His talent was likened to that of Pinetop Smith and other prominent boogie-woogie artists including: Meade Lux Lewis, Cow Cow Davenport and Jimmy Yancey.
